Pregnancy Supplements – prenatal through postpartum

Before pregnancy:

  • Prenatal
    • Dosage: 6 pills/day
      • Magnesium (as magnesium citrate and magnesium aspartate) – 250 mg
      • Vit. D (as cholecalciferol) – 10 mg / 400 IU
      • Folate (as calcium L-5-methyltetrahydrofolate) – 1700 mcg DFE
      • Vit. B12 (as methylcobalamin) – 120 mcg
      • Biotin – 300 mcg
      • Myo-Inositol – 50 mg
  • DHA
    • Brand: Nordic Naturals
    • Dosage: 735 mg EPA/ 525 mg DHA/ Other Omega-3s 240mg
      • Note: The official omega-3 of the American Pregnancy Association is Nordic Naturals’ Prenatal DHA, which provides 480 mg DHA and 205 mg of EPA per serving

During pregnancy:

Same as pre-pregnancy plus:

  • Vitamin D3
    • Brand: vitafusion
    • Form: Cholecalciferaol
    • Dosage: 75 mcg / 3000 IU (2 gummies) daily
    • Studies and notable findings:
      • New insights into the vitamin D requirements during pregnancy (Nature, 2017) It appears crucial to start vitamin D treatment before placentation (formation of the placenta, occurs ~1 week after fertilization)
      • Vitamin D supplementation during pregnancy will decrease asthma or recurrent wheezing rates in children (results reproduced in multiple studies)
      • Strong data suggests a relationship between intrauterine vitamin D deficiency and autism, ADD, bipolar disorder, schizophrenia and impulse behavior all through the control of serotonin synthesis in the neonatal brain
      • A 4,000 IUD (100 mcg) vitamin D3 supplement (10x what was included in my prenatal!) is beneficial to both mother and child
    • Takeaways:
  • Magnesium
    • Brand: Natural Vitality CALM
    • Form: Magnesium citrate
    • Dosage: 165 mg (2 gummies) daily
    • Studies and notable findings:
      • In a randomized clinical trial, women who received 300 mg/day magnesium supplement had decreased preeclampsia (P = 0.018), lower preterm birth (P = 0.044) as well as lower rate of low birth weight (P = 0.002) (Adv Biomed Res. 2017)
  • Choline (started at week 30, but suggest starting by 2nd trimester)
    • Brand: Double Wood Supplements
    • Form: Phosphatidyl-Choline
    • Dosage: 840 mg/day
    • Studies and notable findings:
      • Approximately 90–95% of pregnant women are consuming less than the adequate intake, despite choline’s importance in maternal health (Public Health Nutrition, 2014)
      • Choline is associated with improved cognition and reduced birth defects (cleft palate, neural tube defects) in the fetus, and improved placental and liver function in women (Int J Womens Health, 2013)
      • Dietary supplementation in the second and third trimesters with phosphatidyl-choline is associated with improvement in inhibitory neuronal functions whose deficit is associated with schizophrenia and attention deficit disorder (Shanghai Arch Psychiatry, 2015)
  • Inositol (started at week 30, but suggest starting pre-pregnancy)
    • Brand: Emeritt
    • Form: Myo-inositol, D-Chiro-Inositol
    • Dosage: 2000 mg (2 g) myo-inositol, 50 mg D-chiro-inositol
    • Studies and notable findings:
      • In clinical trials in which inositol dosages ranged from 4 to 60 g/day and the exposure time ranged from 1 to 12 months, the only adverse events reported were mild gastrointestinal symptoms, but only at doses greater of 12 g/day (Diabetes Metab Res Rev, 2019)
      • In women with no previous GDM, <30 BMI, with elevated fasting plasma glucose during 1st trimester, the group treated with 250 mg/day of D-chiro-inositol, 1.75 g/day D-myo-inositol, 12.5 mg/day zinc, 10 mg/day methylsulfonylmethane and 400 mg/day 5-methyltetrahydrofolic acid were found to have significantly lower rates of gestational diabetes at 24 weeks, and their newborns were found to have significantly lower rates of macrosomia (>4kg birth weight) vs. the control group who were treated with only 400 mg/day of folic acid (Biomed Rep, 2017)
    • Takeaways:
      • Inositol supplementation during pregnancy seems to be safe in animal and clinical trials with few adverse effects under 12 g per day
      • In women with no previous diagnosis of GDM, <30 BMI with elevated fasting blood glucose during the 1st trimester, supplement with D-chiro-inositol and D-myo-inositol to lower risk of GDM and macrosomia in newborns

I do also take a probiotic, recommended by my wonderful prenatal chiropractor Dr. Jenny Stofer:

I started this at the beginning of 2nd trimester and will leave the probiotics research for another post!

I will update on post-partum supplements in a few months, but plan to stick to the pregnancy routine at least while breastfeeding.